Cerebrovascular Dysfunction in Amyloid Precursor Protein Transgenic Mice: Contribution of Soluble and Insoluble Amyloid-β Peptide, Partial Restoration via γ-Secretase Inhibition

The contributing effect of cerebrovascular pathology in Alzheimer's disease (AD) has become increasingly appreciated. Recent evidence suggests that amyloid-β peptide (Aβ), the same peptide found in neuritic plaques of AD, may play a role via its vasoactive properties. Several studies have exami...

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Bibliografiset tiedot
Päätekijät: Han, Byung Hee, Zhou, Meng-liang, Abousaleh, Fadi, Brendza, Robert P., Dietrich, Hans H., Koenigsknecht-Talboo, Jessica, Cirrito, John R., Milner, Eric, Holtzman, David M., Zipfel, Gregory J.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Society for Neuroscience 2008
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Articles
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2626633/
https://ncbi.nlm.nih.gov/pubmed/19074028
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4686-08.2008
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