Sorafenib Sensitizes Glioma Cells to the BH3 Mimetic ABT-737 by Targeting MCL1 in a STAT3-Dependent Manner()()

The oncogenic transcription factor signal transducer and activator of transcription 3 (STAT3) is overactivated in malignant glioma and plays a key role in promoting cell survival, thereby increasing the acquired apoptosis resistance of these tumors. Here we investigated the STAT3/myeloid cell leukem...

Full beskrivning

Sparad:
Bibliografiska uppgifter
I publikationen:Neoplasia
Huvudupphovsmän: Kiprianova, Irina, Remy, Janina, Milosch, Nelli, Mohrenz, Isabelle V., Seifert, Volker, Aigner, Achim, Kögel, Donat
Materialtyp: Artigo
Språk:Inglês
Publicerad: Neoplasia Press 2015
Ämnen:
Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4547411/
https://ncbi.nlm.nih.gov/pubmed/26297434
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neo.2015.07.003
Taggar: Lägg till en tagg
Inga taggar, Lägg till första taggen!

Liknande verk