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The BH3 mimetic ABT-737 increases treatment efficiency of paclitaxel against hepatoblastoma

BACKGROUND: The primary goal of current chemotherapy in hepatoblastoma (HB) is reduction of tumour volume and vitality to enable complete surgical resection and reduce risk of recurrence or metastatic disease. Drug resistance remains a major challenge for HB treatment. In some malignancies inhibitio...

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Main Authors: Lieber, Justus, Eicher, Carmen, Wenz, Julia, Kirchner, Bettina, Warmann, Steven W, Fuchs, Jörg, Armeanu-Ebinger, Sorin
格式: Artigo
語言:Inglês
出版: BioMed Central 2011
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3176244/
https://ncbi.nlm.nih.gov/pubmed/21854558
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-11-362
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