The BH3 mimetic ABT-737 increases treatment efficiency of paclitaxel against hepatoblastoma

BACKGROUND: The primary goal of current chemotherapy in hepatoblastoma (HB) is reduction of tumour volume and vitality to enable complete surgical resection and reduce risk of recurrence or metastatic disease. Drug resistance remains a major challenge for HB treatment. In some malignancies inhibitio...

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Bibliographic Details
Main Authors: Lieber, Justus, Eicher, Carmen, Wenz, Julia, Kirchner, Bettina, Warmann, Steven W, Fuchs, Jörg, Armeanu-Ebinger, Sorin
Format: Artigo
Language:Inglês
Published: BioMed Central 2011
Subjects:
Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3176244/
https://ncbi.nlm.nih.gov/pubmed/21854558
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2407-11-362
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