Systemic Administration of siRNA via cRGD-containing Peptide

Although small interfering RNAs (siRNAs) have been demonstrated to specifically silence their target genes in disease models and clinical trials, in vivo siRNA delivery is still the technical bottleneck that limits their use in therapeutic applications. In this study, a bifunctional peptide named RG...

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Bibliografiske detaljer
Udgivet i:Sci Rep
Main Authors: Huang, Yuanyu, Wang, Xiaoxia, Huang, Weiyan, Cheng, Qiang, Zheng, Shuquan, Guo, Shutao, Cao, Huiqing, Liang, Xing-Jie, Du, Quan, Liang, Zicai
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2015
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4547141/
https://ncbi.nlm.nih.gov/pubmed/26300278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep12458
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