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Elimination Pathways of Systemically Delivered siRNA
The elimination process of systemically administered small interfering RNA (siRNA) was investigated by using siRNA labeled with an infrared fluorescent dye. A novel siRNA elimination pathway was identified. In this pathway, liver-enriched siRNA is secreted into the gallbladder and then emptied into...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Nature Publishing Group
2011
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3034859/ https://ncbi.nlm.nih.gov/pubmed/21119623 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2010.266 |
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