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Inter-molecular β-sheet structure facilitates lung-targeting siRNA delivery

Size-dependent passive targeting based on the characteristics of tissues is a basic mechanism of drug delivery. While the nanometer-sized particles are efficiently captured by the liver and spleen, the micron-sized particles are most likely entrapped within the lung owing to its unique capillary str...

詳細記述

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書誌詳細
出版年:Sci Rep
主要な著者: Zhou, Jihan, Li, Dong, Wen, Hao, Zheng, Shuquan, Su, Cuicui, Yi, Fan, Wang, Jue, Liang, Zicai, Tang, Tao, Zhou, Demin, Zhang, Li-He, Liang, Dehai, Du, Quan
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group 2016
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4783658/
https://ncbi.nlm.nih.gov/pubmed/26955887
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep22731
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