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Inter-molecular β-sheet structure facilitates lung-targeting siRNA delivery
Size-dependent passive targeting based on the characteristics of tissues is a basic mechanism of drug delivery. While the nanometer-sized particles are efficiently captured by the liver and spleen, the micron-sized particles are most likely entrapped within the lung owing to its unique capillary str...
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| Publicado en: | Sci Rep |
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| Autores principales: | , , , , , , , , , , , , |
| Formato: | Artigo |
| Lenguaje: | Inglês |
| Publicado: |
Nature Publishing Group
2016
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| Materias: | |
| Acceso en línea: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4783658/ https://ncbi.nlm.nih.gov/pubmed/26955887 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep22731 |
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