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Systemic Administration of siRNA via cRGD-containing Peptide

Although small interfering RNAs (siRNAs) have been demonstrated to specifically silence their target genes in disease models and clinical trials, in vivo siRNA delivery is still the technical bottleneck that limits their use in therapeutic applications. In this study, a bifunctional peptide named RG...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Huang, Yuanyu, Wang, Xiaoxia, Huang, Weiyan, Cheng, Qiang, Zheng, Shuquan, Guo, Shutao, Cao, Huiqing, Liang, Xing-Jie, Du, Quan, Liang, Zicai
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4547141/
https://ncbi.nlm.nih.gov/pubmed/26300278
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/srep12458
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