Protective effect of Gelofusine against cRGD-siRNA-induced nephrotoxicity in mice

Based on successful targeting to the αvβ3 integrin of cyclic arginine–glycine–aspartic acid (cRGD), cRGD-conjugated small interfering RNA (siRNA) exhibits tumor targeting and has become a new treatment strategy for solid tumors. However, the nephrotoxicity caused by its renal retention limits its cl...

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Bibliografische gegevens
Gepubliceerd in:Ren Fail
Hoofdauteurs: Liao, Wenjie, Qin, Yixin, Liao, Lumin, Cen, Bohong, Wu, Zhuomin, Wei, Yuanyi, Wang, Zhen, Li, Guoxian, Ji, Aimin
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Taylor & Francis 2018
Onderwerpen:
Laboratory Study
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6014494/
https://ncbi.nlm.nih.gov/pubmed/29619875
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/0886022X.2018.1450761
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