Gelofusine Attenuates Tubulointerstitial Injury Induced by cRGD-Conjugated siRNA by Regulating the TLR3 Signaling Pathway

Integrin αvβ3, which is selectively targeted by cyclic arginine-glycine-aspartic acid (cRGD) peptides, is significantly upregulated in tumors. Previous studies showed that small interfering RNA (siRNA) modified with cRGD (cRGD-siRNA) could significantly inhibit tumor growth through RNAi with oncogen...

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Publicat a:Mol Ther Nucleic Acids
Autors principals: Cen, Bohong, Liao, Wenjie, Wang, Zhen, Gao, Linyuan, Wei, Yuanyi, Huang, Wen, He, Shuai, Wang, Wei, Liu, Xiaoxia, Pan, Xinghua, Ji, Aimin
Format: Artigo
Idioma:Inglês
Publicat: American Society of Gene & Cell Therapy 2018
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5889698/
https://ncbi.nlm.nih.gov/pubmed/29858065
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omtn.2018.03.006
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