Enhanced Gene Delivery and siRNA Silencing by Gold Nanoparticles Coated with Charge-Reversal Polyelectrolyte

Charge-reversal functional gold nanoparticles first prepared by layer-by-layer technique were employed to deliver small interfering RNA (siRNA) and plasmid DNA into cancer cells. Polyacrylamide gel electrophoresis measurements of siRNA confirmed the occurrence of the charge-reversal property of func...

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Autori principali: Guo, Shutao, Huang, Yuanyu, Jiang, Qiao, Sun, Yun, Deng, Liandong, Liang, Zicai, Du, Quan, Xing, Jinfeng, Zhao, Yuliang, Wang, Paul C., Dong, Anjie, Liang, Xing-Jie
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2010
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3044603/
https://ncbi.nlm.nih.gov/pubmed/20707386
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/nn101638u
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