Age and Amyloid Effects on Human CNS Amyloid-Beta Kinetics

OBJECTIVE: Age is the single greatest risk factor for Alzheimer’s disease with the incidence doubling every 5 years after age 65. However, our understanding of the mechanistic relationship between increasing age and the risk for Alzheimer’s disease is currently limited. We therefore sought to determ...

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發表在:Ann Neurol
Main Authors: Patterson, Bruce W., Elbert, Donald L., Mawuenyega, Kwasi G., Kasten, Tom, Ovod, Vitaliy, Ma, Shengmei, Xiong, Chengjie, Chott, Robert, Yarasheski, Kevin, Sigurdson, Wendy, Zhang, Lily, Goate, Alison, Phil, D., Benzinger, Tammie, Morris, John C., Holtzman, David, Bateman, Randall J.
格式: Artigo
語言:Inglês
出版: 2015
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Article
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4546566/
https://ncbi.nlm.nih.gov/pubmed/26040676
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ana.24454
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