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High-throughput screening by Nuclear Magnetic Resonance (HTS by NMR) for the identification of PPIs antagonists

In recent years the ever so complex field of drug discovery has embraced novel design strategies based on biophysical fragment screening (fragment-based drug design; FBDD) using nuclear magnetic resonance spectroscopy (NMR) and/or structure-guided approaches, most often using X-ray crystallography a...

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Detalhes bibliográficos
Publicado no:Curr Top Med Chem
Main Authors: Wu, Bainan, Barile, Elisa, De, Surya K., Wei, Jun, Purves, Angela, Pellecchia, Maurizio
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4545611/
https://ncbi.nlm.nih.gov/pubmed/25986689
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