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HTS by NMR for the Identification of Potent and Selective Inhibitors of Metalloenzymes

[Image: see text] We have recently proposed a novel drug discovery approach based on biophysical screening of focused positional scanning libraries in which each element of the library contained a common binding moiety for the given target or class of targets. In this Letter, we report on the implem...

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Publicat a:ACS Med Chem Lett
Autors principals: Baggio, Carlo, Cerofolini, Linda, Fragai, Marco, Luchinat, Claudio, Pellecchia, Maurizio
Format: Artigo
Idioma:Inglês
Publicat: American Chemical Society 2018
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC5807865/
https://ncbi.nlm.nih.gov/pubmed/29456802
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsmedchemlett.7b00483
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