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Characterization of the Conjugation Pattern in Large Polysaccharide–Protein Conjugates by NMR Spectroscopy

Carbohydrate‐based vaccines are among the safest and most effective vaccines and represent potent tools for prevention of life‐threatening bacterial infectious diseases, like meningitis and pneumonia. The chemical conjugation of a weak antigen to protein as a source of T‐cell epitopes generates a gl...

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Detalhes bibliográficos
Publicado no:Angew Chem Int Ed Engl
Main Authors: Giuntini, Stefano, Balducci, Evita, Cerofolini, Linda, Ravera, Enrico, Fragai, Marco, Berti, Francesco, Luchinat, Claudio
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5813213/
https://ncbi.nlm.nih.gov/pubmed/29024352
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/anie.201709274
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