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Orientation of immobilized antigens on common surfaces by a simple computational model: Exposition of SARS-CoV-2 Spike protein RBD epitopes

The possibility of immobilizing a protein with antigenic properties on a solid support offers significant possibilities in the development of immunosensors and vaccine formulations. For both applications, the orientation of the antigen should ensure ready accessibility of the antibodies to the epito...

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Detalhes bibliográficos
Publicado no:Biophys Chem
Main Authors: Cerofolini, Linda, Fragai, Marco, Luchinat, Claudio, Ravera, Enrico
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier B.V. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7387289/
https://ncbi.nlm.nih.gov/pubmed/32745829
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpc.2020.106441
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