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High-throughput screening by Nuclear Magnetic Resonance (HTS by NMR) for the identification of PPIs antagonists

In recent years the ever so complex field of drug discovery has embraced novel design strategies based on biophysical fragment screening (fragment-based drug design; FBDD) using nuclear magnetic resonance spectroscopy (NMR) and/or structure-guided approaches, most often using X-ray crystallography a...

詳細記述

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書誌詳細
出版年:Curr Top Med Chem
主要な著者: Wu, Bainan, Barile, Elisa, De, Surya K., Wei, Jun, Purves, Angela, Pellecchia, Maurizio
フォーマット: Artigo
言語:Inglês
出版事項: 2015
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4545611/
https://ncbi.nlm.nih.gov/pubmed/25986689
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