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HTS by NMR guided identification of novel agents targeting the protein docking domain of YopH

Recently we described a novel approach, named HTS by NMR that allows the identification, from large combinatorial peptide libraries, of potent and selective peptide mimetics against a given target. Here we deployed the HTS by NMR approach for the design of novel peptoid sequences targeting the amino...

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Detalhes bibliográficos
Publicado no:ChemMedChem
Main Authors: Bottini, Angel, Wu, Bainan, Barile, Elisa, De, Surya K., Leone, Marilisa, Pellecchia, Maurizio
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4838521/
https://ncbi.nlm.nih.gov/pubmed/26592695
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cmdc.201500441
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