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Design and NMR Studies of Cyclic Peptides Targeting the N-Terminal Domain of the Protein Tyrosine Phosphatase YopH

We report on the design and evaluation of novel cyclic peptides targeting the N-terminal domain of the protein tyrosine phosphatase YopH from Yersinia. Cyclic peptides have been designed based on a short sequence from the protein SKAP-HOM [DE(pY)DDPF (pY = phosphotyrosine)], and they all contain the...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Leone, Marilisa, Barile, Elisa, Dahl, Russell, Pellecchia, Maurizio
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2010
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3149900/
https://ncbi.nlm.nih.gov/pubmed/21118379
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1747-0285.2010.01058.x
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