A carregar...
NMR-based design and evaluation of novel bidentate inhibitors of the protein tyrosine phosphatase YopH
We describe the use of a furanyl salicyl nitroxide derivative (“spin-labeled” compound), as a paramagnetic phosphotyrosine mimetic, to carry out a second-site screening by NMR against the PTPase YopH from Yersinia pestis. Using such a fragment-based screening approach we identified several small mol...
Na minha lista:
| Main Authors: | , , , , , , |
|---|---|
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2010
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2905849/ https://ncbi.nlm.nih.gov/pubmed/20456369 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1747-0285.2010.00982.x |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|