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The Gut-Associated Lymphoid Tissues in the Small Intestine, Not the Large Intestine, Play a Major Role in Oral Prion Disease Pathogenesis

Prion diseases are infectious neurodegenerative disorders characterized by accumulations of abnormally folded cellular prion protein in affected tissues. Many natural prion diseases are acquired orally, and following exposure, the early replication of some prion isolates upon follicular dendritic ce...

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Dades bibliogràfiques
Publicat a:J Virol
Autors principals: Donaldson, David S., Else, Kathryn J., Mabbott, Neil A.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Microbiology 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4542385/
https://ncbi.nlm.nih.gov/pubmed/26157121
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01544-15
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