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The Gut-Associated Lymphoid Tissues in the Small Intestine, Not the Large Intestine, Play a Major Role in Oral Prion Disease Pathogenesis

Prion diseases are infectious neurodegenerative disorders characterized by accumulations of abnormally folded cellular prion protein in affected tissues. Many natural prion diseases are acquired orally, and following exposure, the early replication of some prion isolates upon follicular dendritic ce...

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Bibliografske podrobnosti
izdano v:J Virol
Main Authors: Donaldson, David S., Else, Kathryn J., Mabbott, Neil A.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Microbiology 2015
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4542385/
https://ncbi.nlm.nih.gov/pubmed/26157121
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01544-15
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