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Prion pathogenesis and secondary lymphoid organs (SLO): Tracking the SLO spread of prions to the brain

Prion diseases are subacute neurodegenerative diseases that affect humans and a range of domestic and free-ranging animal species. These diseases are characterized by the accumulation of PrP(Sc), an abnormally folded isoform of the cellular prion protein (PrP(C)), in affected tissues. The pathology...

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Autore principale: Mabbott, Neil A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Landes Bioscience 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3609058/
https://ncbi.nlm.nih.gov/pubmed/22895090
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/pri.20676
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