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Oral Prion Disease Pathogenesis Is Impeded in the Specific Absence of CXCR5-Expressing Dendritic Cells

After oral exposure, the early replication of certain prion strains upon stromal cell-derived follicular dendritic cells (FDC) in the Peyer's patches in the small intestine is essential for the efficient spread of disease to the brain. However, little is known of how prions are initially convey...

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Detalles Bibliográficos
Publicado en:J Virol
Main Authors: Bradford, Barry M., Reizis, Boris, Mabbott, Neil A.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Microbiology 2017
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5411578/
https://ncbi.nlm.nih.gov/pubmed/28275192
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00124-17
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