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Peripheral prion disease pathogenesis is unaltered in the absence of sialoadhesin (Siglec-1/CD169)

Prions are a unique group of pathogens, which are considered to comprise solely of an abnormally folded isoform of the cellular prion protein. The accumulation and replication of prions within secondary lymphoid organs is important for their efficient spread from the periphery to the brain where the...

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Autors principals: Bradford, Barry M, Crocker, Paul R, Mabbott, Neil A
Format: Artigo
Idioma:Inglês
Publicat: BlackWell Publishing Ltd 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4137961/
https://ncbi.nlm.nih.gov/pubmed/24684244
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/imm.12294
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