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Effect of co-infection with a small intestine-restricted helminth pathogen on oral prion disease pathogenesis in mice

The early replication of some orally-acquired prion strains upon stromal-derived follicular dendritic cells (FDC) within the small intestinal Peyer’s patches is essential to establish host infection, and for the disease to efficiently spread to the brain. Factors that influence the early accumulatio...

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Bibliographic Details
Published in:Sci Rep
Main Authors: Sánchez-Quintero, Alejandra, Bradford, Barry M., Maizels, Rick, Donaldson, David S., Mabbott, Neil A.
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2019
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6491469/
https://ncbi.nlm.nih.gov/pubmed/31040320
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-42900-9
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