Assessment of Artificial MiRNA Architectures for Higher Knockdown Efficiencies without the Undesired Effects in Mice

RNAi-based strategies have been used for hypomorphic analyses. However, there are technical challenges to achieve robust, reproducible knockdown effect. Here we examined the artificial microRNA (amiRNA) architectures that could provide higher knockdown efficiencies. Using transient and stable transf...

Descripció completa

Guardat en:
Dades bibliogràfiques
Publicat a:PLoS One
Autors principals: Miura, Hiromi, Inoko, Hidetoshi, Tanaka, Masafumi, Nakaoka, Hirofumi, Kimura, Minoru, Gurumurthy, Channabasavaiah B., Sato, Masahiro, Ohtsuka, Masato
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2015
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4540464/
https://ncbi.nlm.nih.gov/pubmed/26285215
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0135919
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars