Mutation at embB Codon 306, a Potential Marker for the Identification of Multidrug Resistance Associated with Ethambutol in Mycobacterium tuberculosis

Ethambutol inhibits arabinogalactan and lipoarabinomannan biosynthesis in mycobacteria. The occurrence of mutations in embB codon 306 in ethambutol-susceptible isolates and their absence in resistant isolates has raised questions regarding the utility of this codon as a potential marker for resistan...

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Vydáno v:Antimicrob Agents Chemother
Hlavní autoři: Cuevas-Córdoba, Betzaida, Juárez-Eusebio, Dulce María, Almaraz-Velasco, Raquel, Muñiz-Salazar, Raquel, Laniado-Laborin, Rafael, Zenteno-Cuevas, Roberto
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2015
Témata:
Mechanisms of Resistance
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4538480/
https://ncbi.nlm.nih.gov/pubmed/26124153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00117-15
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