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Mutations at embB Codon 306 Are an Important Molecular Indicator of Ethambutol Resistance in Mycobacterium tuberculosis

Ethambutol resistance in clinical Mycobacterium tuberculosis isolates is associated primarily with missense mutations in the embB gene. However, recent reports have described the presence of embB mutations, especially those at embB codon 306, in isolates susceptible to ethambutol. To clarify the rol...

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Detalhes bibliográficos
Main Authors: Starks, Angela M., Gumusboga, Aysel, Plikaytis, Bonnie B., Shinnick, Thomas M., Posey, James E.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2650568/
https://ncbi.nlm.nih.gov/pubmed/19104018
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01357-08
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