Transfer of embB Codon 306 Mutations into Clinical Mycobacterium tuberculosis Strains Alters Susceptibility to Ethambutol, Isoniazid, and Rifampin

Implicated as a major mechanism of ethambutol (EMB) resistance in clinical studies of Mycobacterium tuberculosis, mutations in codon 306 of the embB gene (embB306) have also been detected in EMB-susceptible clinical isolates. Other studies have found strong associations between embB306 mutations and...

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Hlavní autoři: Safi, Hassan, Sayers, Brendan, Hazbón, Manzour H., Alland, David
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology (ASM) 2008
Témata:
Mechanisms of Resistance
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2415778/
https://ncbi.nlm.nih.gov/pubmed/18378710
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01486-07
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