Significance of Mutations in embB Codon 306 for Prediction of Ethambutol Resistance in Clinical Mycobacterium tuberculosis Isolates

We analyzed 159 Mycobacterium tuberculosis isolates (101 ethambutol [EMB]-resistant strains, 33 multidrug-resistant but not EMB-resistant strains, and 25 fully susceptible strains) for the presence of mutations in embB codon 306 (embB306). Mutations were detected only in EMB-resistant strains (n = 6...

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Autores principales: Plinke, Claudia, Rüsch-Gerdes, Sabine, Niemann, Stefan
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2006
Materias:
Mechanisms of Resistance
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1472212/
https://ncbi.nlm.nih.gov/pubmed/16641474
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.50.5.1900-1902.2006
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