Mutation at embB Codon 306, a Potential Marker for the Identification of Multidrug Resistance Associated with Ethambutol in Mycobacterium tuberculosis

Ethambutol inhibits arabinogalactan and lipoarabinomannan biosynthesis in mycobacteria. The occurrence of mutations in embB codon 306 in ethambutol-susceptible isolates and their absence in resistant isolates has raised questions regarding the utility of this codon as a potential marker for resistan...

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Foilsithe in:Antimicrob Agents Chemother
Main Authors: Cuevas-Córdoba, Betzaida, Juárez-Eusebio, Dulce María, Almaraz-Velasco, Raquel, Muñiz-Salazar, Raquel, Laniado-Laborin, Rafael, Zenteno-Cuevas, Roberto
Formáid: Artigo
Teanga:Inglês
Foilsithe: American Society for Microbiology 2015
Ábhair:
Mechanisms of Resistance
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4538480/
https://ncbi.nlm.nih.gov/pubmed/26124153
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00117-15
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