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Stimulation of the cardiac myocyte Na(+)-K(+) pump due to reversal of its constitutive oxidative inhibition

Protein kinase C can activate NADPH oxidase and induce glutathionylation of the β(1)-Na(+)-K(+) pump subunit, inhibiting activity of the catalytic α-subunit. To examine if signaling of nitric oxide-induced soluble guanylyl cyclase (sGC)/cGMP/protein kinase G can cause Na(+)-K(+) pump stimulation by...

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Detalhes bibliográficos
Publicado no:Am J Physiol Cell Physiol
Main Authors: Chia, Karin K. M., Liu, Chia-Chi, Hamilton, Elisha J., Garcia, Alvaro, Fry, Natasha A., Hannam, William, Figtree, Gemma A., Rasmussen, Helge H.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4537930/
https://ncbi.nlm.nih.gov/pubmed/26084308
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajpcell.00392.2014
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