Protein kinase-dependent oxidative regulation of the cardiac Na(+)–K(+) pump: evidence from in vivo and in vitro modulation of cell signalling

The widely reported stimulation of the cardiac Na(+)–K(+) pump by protein kinase A (PKA) should oppose other effects of PKA to increase contractility of the normal heart. It should also reduce harmful raised myocyte Na(+) levels in heart failure, yet blockade of the β(1) adrenergic receptor (AR), co...

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Detalhes bibliográficos
Main Authors: Galougahi, Keyvan Karimi, Liu, Chia-Chi, Garcia, Alvaro, Fry, Natasha A S, Hamilton, Elisha J, Rasmussen, Helge H, Figtree, Gemma A
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2013
Assuntos:
Cardiovascular
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3832116/
https://ncbi.nlm.nih.gov/pubmed/23587884
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2013.252817
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