FXYD Proteins Reverse Inhibition of the Na(+)-K(+) Pump Mediated by Glutathionylation of Its β(1) Subunit

The seven members of the FXYD protein family associate with the Na(+)-K(+) pump and modulate its activity. We investigated whether conserved cysteines in FXYD proteins are susceptible to glutathionylation and whether such reactivity affects Na(+)-K(+) pump function in cardiac myocytes and Xenopus oo...

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Autors principals: Bibert, Stéphanie, Liu, Chia-Chi, Figtree, Gemma A., Garcia, Alvaro, Hamilton, Elisha J., Marassi, Francesca M., Sweadner, Kathleen J., Cornelius, Flemming, Geering, Käthi, Rasmussen, Helge H.
Format: Artigo
Idioma:Inglês
Publicat: American Society for Biochemistry and Molecular Biology 2011
Matèries:
Membrane Biology
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3099672/
https://ncbi.nlm.nih.gov/pubmed/21454534
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M110.184101
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