IQGAP1 and IQGAP3 serve individually essential roles in normal epidermal homeostasis and tumor progression

IQGAP scaffolding proteins regulate many essential cellular processes including growth factor receptor signaling, cytoskeletal rearrangement, adhesion and proliferation, and are highly expressed in many cancers. Using genetically engineered human skin tissue in vivo, we demonstrate that diminished,...

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Detaylı Bibliyografya
Yayımlandı:J Invest Dermatol
Asıl Yazarlar: Monteleon, Christine L., McNeal, Andrew, Duperret, Elizabeth K., Oh, Seung Ja, Schapira, Emily, Ridky, Todd W.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2015
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4537348/
https://ncbi.nlm.nih.gov/pubmed/25848980
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jid.2015.140
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