IQGAP1 and IQGAP3 serve individually essential roles in normal epidermal homeostasis and tumor progression

IQGAP scaffolding proteins regulate many essential cellular processes including growth factor receptor signaling, cytoskeletal rearrangement, adhesion and proliferation, and are highly expressed in many cancers. Using genetically engineered human skin tissue in vivo, we demonstrate that diminished,...

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Библиографические подробности
Опубликовано в: :J Invest Dermatol
Главные авторы: Monteleon, Christine L., McNeal, Andrew, Duperret, Elizabeth K., Oh, Seung Ja, Schapira, Emily, Ridky, Todd W.
Формат: Artigo
Язык:Inglês
Опубликовано: 2015
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4537348/
https://ncbi.nlm.nih.gov/pubmed/25848980
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jid.2015.140
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