IQGAP1 and IQGAP3 serve individually essential roles in normal epidermal homeostasis and tumor progression

IQGAP scaffolding proteins regulate many essential cellular processes including growth factor receptor signaling, cytoskeletal rearrangement, adhesion and proliferation, and are highly expressed in many cancers. Using genetically engineered human skin tissue in vivo, we demonstrate that diminished,...

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Dettagli Bibliografici
Pubblicato in:J Invest Dermatol
Autori principali: Monteleon, Christine L., McNeal, Andrew, Duperret, Elizabeth K., Oh, Seung Ja, Schapira, Emily, Ridky, Todd W.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2015
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4537348/
https://ncbi.nlm.nih.gov/pubmed/25848980
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jid.2015.140
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