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IQGAP1 and IQGAP3 serve individually essential roles in normal epidermal homeostasis and tumor progression
IQGAP scaffolding proteins regulate many essential cellular processes including growth factor receptor signaling, cytoskeletal rearrangement, adhesion and proliferation, and are highly expressed in many cancers. Using genetically engineered human skin tissue in vivo, we demonstrate that diminished,...
Uloženo v:
| Vydáno v: | J Invest Dermatol |
|---|---|
| Hlavní autoři: | , , , , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
2015
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4537348/ https://ncbi.nlm.nih.gov/pubmed/25848980 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jid.2015.140 |
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