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IQGAP1 and IQGAP3 serve individually essential roles in normal epidermal homeostasis and tumor progression
IQGAP scaffolding proteins regulate many essential cellular processes including growth factor receptor signaling, cytoskeletal rearrangement, adhesion and proliferation, and are highly expressed in many cancers. Using genetically engineered human skin tissue in vivo, we demonstrate that diminished,...
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| 出版年: | J Invest Dermatol |
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| 主要な著者: | , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2015
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4537348/ https://ncbi.nlm.nih.gov/pubmed/25848980 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/jid.2015.140 |
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