A molecular tweezer antagonizes seminal amyloids and HIV infection

Semen is the main vector for HIV transmission and contains amyloid fibrils that enhance viral infection. Available microbicides that target viral components have proven largely ineffective in preventing sexual virus transmission. In this study, we establish that CLR01, a ‘molecular tweezer’ specific...

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Detaylı Bibliyografya
Yayımlandı:eLife
Asıl Yazarlar: Lump, Edina, Castellano, Laura M, Meier, Christoph, Seeliger, Janine, Erwin, Nelli, Sperlich, Benjamin, Stürzel, Christina M, Usmani, Shariq, Hammond, Rebecca M, von Einem, Jens, Gerold, Gisa, Kreppel, Florian, Bravo-Rodriguez, Kenny, Pietschmann, Thomas, Holmes, Veronica M, Palesch, David, Zirafi, Onofrio, Weissman, Drew, Sowislok, Andrea, Wettig, Burkhard, Heid, Christian, Kirchhoff, Frank, Weil, Tanja, Klärner, Frank-Gerrit, Schrader, Thomas, Bitan, Gal, Sanchez-Garcia, Elsa, Winter, Roland, Shorter, James, Münch, Jan
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: eLife Sciences Publications, Ltd 2015
Konular:
Biochemistry
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4536748/
https://ncbi.nlm.nih.gov/pubmed/26284498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.05397
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