A molecular tweezer antagonizes seminal amyloids and HIV infection

Semen is the main vector for HIV transmission and contains amyloid fibrils that enhance viral infection. Available microbicides that target viral components have proven largely ineffective in preventing sexual virus transmission. In this study, we establish that CLR01, a ‘molecular tweezer’ specific...

詳細記述

保存先:
書誌詳細
出版年:eLife
主要な著者: Lump, Edina, Castellano, Laura M, Meier, Christoph, Seeliger, Janine, Erwin, Nelli, Sperlich, Benjamin, Stürzel, Christina M, Usmani, Shariq, Hammond, Rebecca M, von Einem, Jens, Gerold, Gisa, Kreppel, Florian, Bravo-Rodriguez, Kenny, Pietschmann, Thomas, Holmes, Veronica M, Palesch, David, Zirafi, Onofrio, Weissman, Drew, Sowislok, Andrea, Wettig, Burkhard, Heid, Christian, Kirchhoff, Frank, Weil, Tanja, Klärner, Frank-Gerrit, Schrader, Thomas, Bitan, Gal, Sanchez-Garcia, Elsa, Winter, Roland, Shorter, James, Münch, Jan
フォーマット: Artigo
言語:Inglês
出版事項: eLife Sciences Publications, Ltd 2015
主題:
Biochemistry
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4536748/
https://ncbi.nlm.nih.gov/pubmed/26284498
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.05397
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