載入...
Absence of both Sos-1 and Sos-2 in peripheral CD4(+) T cells leads to PI3K pathway activation and defects in migration
Sos-1 and Sos-2 are ubiquitously expressed Ras-Guanine Exchange Factors involved in Erk-MAP kinase pathway activation. Using mice lacking genes encoding Sos-1 and Sos-2, we evaluated the role of these proteins in peripheral T-cell signaling and function. Our results confirmed that TCR-mediated Erk a...
Na minha lista:
| 發表在: | Eur J Immunol |
|---|---|
| Main Authors: | , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2015
|
| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4536155/ https://ncbi.nlm.nih.gov/pubmed/25973715 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/eji.201445226 |
| 標簽: |
添加標簽
沒有標簽, 成為第一個標記此記錄!
|