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Conformational Differences between Open and Closed States of the Eukaryotic Translation Initiation Complex
Translation initiation in eukaryotes begins with the formation of a pre-initiation complex (PIC) containing the 40S ribosomal subunit, eIF1, eIF1A, eIF3, ternary complex (eIF2-GTP-Met-tRNA(i)), and eIF5. The PIC, in an open conformation, attaches to the 5′ end of the mRNA and scans to locate the sta...
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| Udgivet i: | Mol Cell |
|---|---|
| Main Authors: | , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Cell Press
2015
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4534855/ https://ncbi.nlm.nih.gov/pubmed/26212456 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2015.06.033 |
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