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Current Approaches for Investigating and Predicting Cytochrome P450 3A4-Ligand Interactions
Cytochrome P450 3A4 (CYP3A4) is the major and most important drug-metabolizing enzyme in humans that oxidizes and clears over a half of all administered pharmaceuticals. This is possible because CYP3A4 is promiscuous with respect to substrate binding and has the ability to catalyze diverse oxidative...
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| 出版年: | Adv Exp Med Biol |
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| 主要な著者: | , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2015
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4532289/ https://ncbi.nlm.nih.gov/pubmed/26002732 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-3-319-16009-2_3 |
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