Engineering Human Stem Cell Lines with Inducible Gene Knockout using CRISPR/Cas9

Precise temporal control of gene expression or deletion is critical for elucidating gene function in biological systems. However, establishment of human pluripotent stem cell (hPSC) lines with inducible gene knockout (iKO) remains challenging. We explored building iKO hPSC lines by combining CRISPR/...

Volledige beschrijving

Bewaard in:
Bibliografische gegevens
Gepubliceerd in:Cell Stem Cell
Hoofdauteurs: Chen, Yuejun, Cao, Jingyuan, Xiong, Man, Petersen, Andrew J., Dong, Yi, Tao, Yunlong, Huang, Cindy Tzu-Ling, Du, Zhongwei, Zhang, Su-Chun
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2015
Onderwerpen:
Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4530040/
https://ncbi.nlm.nih.gov/pubmed/26145478
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2015.06.001
Tags: Voeg label toe
Geen labels, Wees de eerste die dit record labelt!

Gelijkaardige items