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Using CRISPR/Cas9 for Gene Knockout in Immunodeficient NSG Mice
NOD.Cg-Prkdc(scid) Il2rg(tm1Wjl/)SzJ (NSG) mice are an immunodeficient strain that enables human cell xenografts. However, NSG mice possess a complex genetic background that would complicate cross-breeding with other inbred transgenic or knockout mouse strains to establish a congenic strain with a d...
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| 出版年: | Methods Mol Biol |
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| 主要な著者: | , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2019
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7467215/ https://ncbi.nlm.nih.gov/pubmed/30353512 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-4939-8831-0_8 |
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