Engineering Human Stem Cell Lines with Inducible Gene Knockout using CRISPR/Cas9

Precise temporal control of gene expression or deletion is critical for elucidating gene function in biological systems. However, establishment of human pluripotent stem cell (hPSC) lines with inducible gene knockout (iKO) remains challenging. We explored building iKO hPSC lines by combining CRISPR/...

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Detaylı Bibliyografya
Yayımlandı:Cell Stem Cell
Asıl Yazarlar: Chen, Yuejun, Cao, Jingyuan, Xiong, Man, Petersen, Andrew J., Dong, Yi, Tao, Yunlong, Huang, Cindy Tzu-Ling, Du, Zhongwei, Zhang, Su-Chun
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2015
Konular:
Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4530040/
https://ncbi.nlm.nih.gov/pubmed/26145478
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.stem.2015.06.001
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