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More powerful virus inhibitors from structure-based analysis of HEV71 capsid-binding molecules
Enterovirus 71 (HEV71) epidemics amongst children and infants result mainly in mild symptoms, however, especially in the Asia-Pacific region, infection can be fatal. At present no therapies are available. We have used structural analysis of the complete virus to guide the design of HEV71 inhibitors....
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| Publicado no: | Nat Struct Mol Biol |
|---|---|
| Main Authors: | , , , , , , , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4530014/ https://ncbi.nlm.nih.gov/pubmed/24509833 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.2769 |
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