A sensor-adaptor mechanism for enterovirus uncoating from structures of EV71

Enterovirus 71 (EV71), a major agent of hand-foot-and-mouth disease in children, can cause severe central nervous system disease and mortality. At present no vaccine or antiviral therapy is available. We have determined high-resolution structures for the mature virus and natural empty particles. The...

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Detalhes bibliográficos
Main Authors: Wang, Xiangxi, Peng, Wei, Ren, Jingshan, Hu, Zhongyu, Xu, Jiwei, Lou, Zhiyong, Li, Xumei, Yin, Weidong, Shen, Xinliang, Porta, Claudine, Walter, Thomas S., Evans, Gwyndaf, Axford, Danny, Owen, Robin, Rowlands, David J., Wang, Junzhi, Stuart, David I., Fry, Elizabeth E., Rao, Zihe
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3378640/
https://ncbi.nlm.nih.gov/pubmed/22388738
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nsmb.2255
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