Efficacy of topical tenofovir against transmission of a tenofovir-resistant SHIV in macaques

BACKGROUND: Topically delivered tenofovir (TFV) from intravaginal rings, tablets, or gels is being evaluated for HIV prevention. We previously demonstrated that TFV delivered vaginally by gel protected macaques from vaginal infection with SHIV. Here we investigated efficacy of the TFV gel against va...

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Bibliographic Details
Published in:Retrovirology
Main Authors: Dobard, Charles W, Sharma, Sunita, Cong, Mian-er, West, Rolieria, Makarova, Natalia, Holder, Angela, Pau, Chou-Pong, Hanson, Debra L., Novembre, Francis J, Garcia-Lerma, Jose Gerardo, Heneine, Walid
Format: Artigo
Language:Inglês
Published: BioMed Central 2015
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Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4528693/
https://ncbi.nlm.nih.gov/pubmed/26253002
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12977-015-0195-z
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