Prophylactic Efficacy of Oral Emtricitabine and Tenofovir Disoproxil Fumarate Combination Therapy Against a Tenofovir-Resistant Simian/Human Immunodeficiency Virus Containing the K65R Mutation in Macaques

Daily preexposure prophylaxis (PrEP) with emtricitabine/tenofovir disoproxil fumarate (FTC/TDF) is a novel strategy for preventing human immunodeficiency virus infection. We investigated in macaques whether FTC/TDF prevents transmission of a tenofovir-resistant simian/human immunodeficiency virus (S...

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Detalhes bibliográficos
Main Authors: Cong, Mian-er, Mitchell, James, Sweeney, Elizabeth, Bachman, Shanon, Hanson, Debra L., Heneine, Walid, García-Lerma, J. Gerardo
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2013
Assuntos:
Major Articles and Brief Reports
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3699008/
https://ncbi.nlm.nih.gov/pubmed/23633402
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jit189
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